Serum for Acne Scars: Complete Guide to Treatment Options
- Chikako Oka
- Dec 1, 2025
- 7 min read
Acne scars can persist long after breakouts have cleared, affecting both skin texture and confidence. While various treatment options exist, serums have gained attention as accessible at-home skincare solutions. This guide explores what serums may offer for acne scar management, their key ingredients, and how they compare to professional treatments.

Understanding Acne Scars and Treatment Approaches
What Are Acne Scars?
Acne scars form when inflammatory acne damages the skin's deeper layers, disrupting normal collagen production during the healing process. Unlike temporary post-inflammatory marks that fade over time, true acne scars involve permanent changes to skin structure.
Types of Acne Scars
Acne scars are classified into distinct categories based on their appearance and formation:
Atrophic Scars develop when insufficient collagen is produced during healing, creating depressions in the skin. These include ice pick scars (deep, narrow pits), boxcar scars (wider depressions with defined edges), and rolling scars (wave-like undulations caused by fibrous bands beneath the skin).
Hypertrophic and Keloid Scars result from excess collagen production, forming raised areas on the skin surface. Keloid scars extend beyond the original acne site and are more common in individuals with darker skin tones.
Post-Inflammatory Changes include hyperpigmentation (darkened marks) and erythema (redness), which are not true scars but temporary discolouration that may resolve without intervention.
Can Serums Address Acne Scars?
The potential of serums to improve acne scars depends significantly on the scar type and severity. Serums may help with superficial texture irregularities and post-inflammatory discolouration through ingredients that support skin cell turnover and collagen synthesis. However, deeper structural scars typically require professional interventions such as laser treatments, microneedling, or subcision for meaningful improvement.
Understanding these distinctions helps set realistic expectations when considering serum-based approaches as part of a comprehensive skincare strategy.
Key Ingredients in Acne Scar Serums

Vitamin C (L-Ascorbic Acid)
Vitamin C functions as an antioxidant and cofactor in collagen synthesis. Some formulations may help reduce post-inflammatory hyperpigmentation by interfering with melanin production. Research suggests that vitamin C in stable formulations can support skin brightening, though results vary among individuals. For optimal stability, look for concentrations between 10-20% in formulations with pH below 3.5.
Retinoids (Vitamin A Derivatives)
Retinoids, including prescription tretinoin and over-the-counter retinol, promote cellular turnover and may stimulate collagen production over time. Studies indicate that long-term retinoid use can improve skin texture and reduce the appearance of superficial scarring, though the degree of improvement differs among users. Retinoids require gradual introduction to minimize irritation, typically starting with 2-3 applications per week.
Niacinamide (Vitamin B3)
Niacinamide offers multiple skin benefits, including supporting the skin barrier, reducing inflammation, and potentially helping to fade post-inflammatory hyperpigmentation. Clinical studies have examined concentrations of 2-5% for various skin concerns. This ingredient is generally well-tolerated and suitable for sensitive skin types.
Alpha Hydroxy Acids (AHAs)
AHAs such as glycolic acid and lactic acid work by promoting exfoliation of the outermost skin layer, which may improve surface texture and tone over time. Glycolic acid, with its small molecular size, can penetrate effectively. Formulations typically range from 5-10% for at-home use, while professional treatments may use higher concentrations.
Hyaluronic Acid
While hyaluronic acid does not directly modify scar structure, it provides hydration by attracting moisture to the skin. Well-hydrated skin may appear plumper and smoother, potentially making scars less noticeable. This ingredient is suitable for all skin types and can be used alongside other active ingredients.
Peptides
Peptides are amino acid chains that may signal collagen production in the skin. Some evidence suggests certain peptides can support skin repair processes, though more research is needed to confirm their effectiveness specifically for acne scarring. Common peptides in skincare include palmitoyl pentapeptide and copper peptides.

Professional Treatments for Acne Scars
While serums can play a supportive role in skincare routines, professional treatments often provide more substantial results for moderate to severe acne scarring.
Laser and Energy-Based Treatments
Fractional CO2 Laser creates controlled micro-injuries in the skin, stimulating collagen remodelling and new tissue formation. This treatment is particularly studied for atrophic scars, though it requires downtime for healing and carries risks of temporary pigmentation changes.
Pulsed Dye Laser (such as Vbeam) targets blood vessels and may help reduce redness associated with acne scars and active acne. Multiple sessions are typically needed, and results vary based on individual response.
Radiofrequency Microneedling combines physical needling with radiofrequency energy to stimulate collagen production at various skin depths. This approach has been examined for improving scar texture and depth.
Physical Resurfacing Procedures
Microneedling involves creating controlled micro-channels in the skin using fine needles, triggering the body's wound healing response. Studies have investigated this procedure for improving acne scar appearance, particularly when combined with topical growth factors or platelet-rich plasma.
Chemical Peels use controlled chemical solutions to remove damaged outer skin layers. Medium-depth peels using trichloroacetic acid (TCA) have been studied for atrophic acne scars, though results depend on scar type and depth.
Subcision is a minor surgical procedure where a needle is inserted beneath scars to release fibrous bands that tether skin downward. This technique specifically addresses rolling scars and may be combined with other treatments for enhanced outcomes.
Injectable Treatments
Dermal Fillers can temporarily elevate depressed scars, providing immediate improvement in skin contour. Results typically last several months to over a year, depending on the filler type and individual factors.
Selecting Appropriate Products and Treatments
Assessing Your Skin Type and Scar Severity
Before selecting any treatment approach, consider your skin's characteristics and the nature of your scarring. Sensitive skin may react to high concentrations of active ingredients, while oily skin might tolerate stronger formulations. The depth, type, and extent of scarring also influence which treatments may be most suitable.
Building an Effective Skincare Routine
When incorporating serums into your routine, consider the following structure:
Morning Routine: Begin with a gentle cleanser, apply antioxidant serum (such as vitamin C), follow with moisturizer, and finish with broad-spectrum sunscreen of SPF 30 or higher.
Evening Routine: Cleanse thoroughly, apply treatment serum (such as retinoid or AHA), follow with moisturizer, and consider layering with hyaluronic acid for added hydration.
Introduce new active ingredients gradually, monitoring for irritation. Avoid combining multiple exfoliating or potentially irritating ingredients simultaneously, as this can compromise the skin barrier.
The Importance of Sun Protection
Sun exposure can worsen hyperpigmentation and interfere with scar healing. Many active ingredients, particularly retinoids and AHAs, increase photosensitivity. Daily application of broad-spectrum sunscreen is essential when using these treatments, regardless of weather conditions.
Treatment Timeline and Expectations
Realistic Timeframes for Results
Skincare treatments work gradually, and patience is important when addressing acne scars. Surface improvements in skin texture and tone may become noticeable within 4-8 weeks of consistent serum use, though individual responses vary. More significant changes in scar appearance typically require 3-6 months of regular application or multiple professional treatment sessions.
Professional treatments like laser therapy or microneedling often involve a series of sessions spaced several weeks apart, with continued improvement occurring over several months as collagen remodelling progresses.
Factors Influencing Treatment Outcomes
Several variables affect how individuals respond to scar treatments, including age, overall skin health, scar depth and type, consistency of product use, and adherence to sun protection. Genetic factors and individual healing responses also play important roles in treatment results.
Monitoring Progress
Documenting your skin's appearance with photographs taken in consistent lighting can help track changes over time. Since improvements occur gradually, these reference points can be valuable in assessing treatment effectiveness.
Combining Approaches for Comprehensive Care
Integrated Treatment Strategies
Many individuals find that combining professional treatments with consistent at-home skincare provides more comprehensive results than either approach alone. For example, professional treatments can address deeper structural issues, while daily serum use supports ongoing skin health and may help maintain treatment results.
Professional Consultation
A doctor or qualified skincare professional can assess your specific scarring pattern and recommend a personalized treatment plan. They can identify which scar types are present, suggest appropriate professional procedures, and guide you in selecting complementary at-home products.
Managing Expectations
While modern treatments offer various options for improving acne scars, complete removal of all scarring may not be achievable in every case. Setting realistic goals focused on improvement rather than perfection can help maintain a positive perspective throughout the treatment journey.
Safety Considerations and Potential Reactions
Common Side Effects of Active Ingredients
Topical treatments may cause temporary reactions as skin adjusts to active ingredients. Retinoids and AHAs commonly cause mild dryness, redness, or flaking, particularly during initial use. These effects often diminish as skin builds tolerance over several weeks.
Niacinamide and hyaluronic acid are generally well-tolerated, though any skincare product can potentially cause reactions in sensitive individuals. If persistent irritation, severe redness, or unusual symptoms occur, discontinue use and consult with a healthcare professional.
Professional Treatment Considerations
Professional procedures carry specific considerations, including temporary redness, swelling, or skin sensitivity following treatment. More intensive procedures like fractional lasers may involve several days of healing time. Your treatment provider should discuss expected recovery periods and any specific aftercare requirements.
When to Seek Professional Guidance
Consult with a dermatologist or qualified skincare professional if you experience persistent skin reactions, notice changes in existing scars, have concerns about new skin changes, or feel uncertain about which treatments might be appropriate for your situation.
Conclusion
Serums containing ingredients like vitamin C, retinoids, niacinamide, and AHAs may support skin health and contribute to improvements in skin texture and post-inflammatory discolouration. However, their impact on deeper structural acne scars is typically limited compared to professional interventions.
For individuals seeking to address acne scarring, a combination of consistent at-home skincare and professionally administered treatments often provides the most comprehensive approach. Individual results vary, and there is no universal solution that works identically for everyone.
If you are considering treatment for acne scars, consulting with a qualified dermatologist or skincare professional can help you develop a personalized plan tailored to your specific skin type, scar characteristics, and treatment goals.
Note: This article is for educational purposes only and does not constitute medical advice. Individual treatment plans should be developed in consultation with qualified healthcare professionals. Treatment outcomes vary from person to person, and no guarantee of results is intended or implied. All professional treatments mentioned should be performed by licensed medical practitioners in Singapore, using HSA-approved products, devices, and techniques, as applicable.